RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-29a
RNA ID
MI0000087
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
PI3K; AKT
Pathway
PI4K-AKT SIGNALING PATHWAY
PubMed ID
25356754
Title
MicroRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway
Year
2015
Function
Microrna-29b prevents hepatic fibrosis by reducing hepatic stellate cell activation and inducing apoptosis by targeting the pi3k ; Akt pathway.